Many keyboard shortcuts are configurable via Preference Window (click [Windows]/[Preferences] in Eclipse main menu), the preference page to configure keyboard shortcuts (or so called "hotkey") is located in General/Keys preference page.

Refer to the "Customizing Key bindings" section of Eclipse official help:

http://help.eclipse.org/ganymede/topic/org.eclipse.platform.doc.user/concepts/accessibility/keyboardshortcuts.htm